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6-Fluorotryptophan

CAS: 7730-20-3 F: C11H11FN2O2 W: 222.22

6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats
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Bioactivity 6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes[1].
Name 6-Fluorotryptophan
CAS 7730-20-3
Formula C11H11FN2O2
Molar Mass 222.22
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reference [1]. Miwa S, et al. Determination of serotonin turnover in the rat brain using 6-fluorotryptophan. J Neurochem. 1987 May;48(5):1577-80. [2]. D Sugden, et al. Changes in the rat sleep-wake cycle produced by DL-6-fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase. Psychopharmacology (Berl). 1981;74(4):369-73.