| Bioactivity | 6,6′-Dihydroxythiobinupharidine is a cysteine proteases inhibitor. 6,6′-Dihydroxythiobinupharidine can enhance DNA cleavage mediated by human topoisomerase IIα and IIβ ~8-fold and ~3-fold, respectively[1][2]. |
| Name | 6,6′-Dihydroxythiobinupharidine |
| CAS | 30343-70-5 |
| Formula | C30H42N2O4S |
| Molar Mass | 526.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. YamaharaJ, et al. Potent immunosuppressive principles, dimeric sesquiterpenethioalkaloids, isolated from nupharis rhizoma, the rhizoma of Nuphar pumilum(nymphaeaceae): structure-requirement of nuphar-alkaloid for immunosuppressiveactivity. Biol Pharm Bull. 1996;19(9):1241-1243. [2]. DalvieED, et al. 6,6'-Dihydroxythiobinupharidine as a poison of human type IItopoisomerases. Bioorg Med Chem Lett. 2019;29(15):1881-1885. |
6,6′-Dihydroxythiobinupharidine
CAS: 30343-70-5 F: C30H42N2O4S W: 526.73
6,6′-Dihydroxythiobinupharidine is a cysteine proteases inhibitor. 6,6′-Dihydroxythiobinupharidine can enhance DNA cle
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