| Bioactivity | FRATtide is a peptide derived from the GSK-3 binding protein that inhibits the phosphorylation of Axin and β-catenin. FRATtide inhibits GSK-3 binding to Axin[1]. |
| Name | FRATtide |
| CAS | 251087-38-4 |
| Sequence | Ser-Gln-Pro-Glu-Thr-Arg-Thr-Gly-Asp-Asp-Asp-Pro-His-Arg-Leu-Leu-Gln-Gln-Leu-Val-Leu-Ser-Gly-Asn-Leu-Ile-Lys-Glu-Ala-Val-Arg-Arg-Leu-His-Ser-Arg-Arg-Leu-Gln |
| Shortening | SQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQ |
| Formula | C192H327N67O60 |
| Molar Mass | 4534.06 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bax B, et al. The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation. Structure. 2001 Dec;9(12):1143-52. |
FRATtide
CAS: 251087-38-4 F: C192H327N67O60 W: 4534.06
FRATtide is a peptide derived from the GSK-3 binding protein that inhibits the phosphorylation of Axin and β-catenin. F
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