Bioactivity | 4'-trans-Hydroxy Cilostazol-d4 is deuterated labeled 4'-trans-Hydroxy Cilostazol (HY-137215). 4'-trans-Hydroxy Cilostazol is a metabolite of Cilostazol[1]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 4'-trans-Hydroxy Cilostazol-d4 相关抗体: |
Formula | C20H23D4N5O3 |
Molar Mass | 389.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Weng Q, et, al. Effect of Baicalein on the Pharmacokinetics of Cilostazol and Its Two Metabolites in Rat Plasma Using UPLC-MS/MS Method. Front Pharmacol. 2022 Apr 27;13:888054. |