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(10E,12Z)-Octadeca-10,12-dienoic acid

CAS: 2420-56-6 F: C18H32O2 W: 280.45

(10E,12Z)-Octadeca-10,12-dienoic acidactivates PPAR α and inhibits adipocyte differentiation. (10E,12Z)-Octadeca-10,12-
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Bioactivity (10E,12Z)-Octadeca-10,12-dienoic acidactivates PPAR α and inhibits adipocyte differentiation[1]. (10E,12Z)-Octadeca-10,12-dienoic acid and its downstream metabolites have various antioxidant and antitumor activities. (10E,12Z)-Octadeca-10,12-dienoic acid is effective orally[2][3].
CAS 2420-56-6
Formula C18H32O2
Molar Mass 280.45
Appearance 液体
Transport Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Houseknecht KL, et al. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochem Biophys Res Commun. 1998 Mar 27;244(3):678-82. [2]. Shultz TD, et al.Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells. Cancer Lett. 1992 Apr 15;63(2):125-33.  [3]. Park Y, et al Conjugated fatty acids as a prevention tool for obesity and osteoporosis[M]//Emerging trends in dietary components for preventing and combating disease. American Chemical Society, 2012: 393-405