| Bioactivity | 4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1]. | |||||||||
| Invitro | 4-thiouridine (0-10 μM) labels and purifies nascent rRNA without significantly affecting rRNA synthesis[1].4-thiouridine (≥50 μM) strongly inhibits production and processing of rRNA[1]. | |||||||||
| Name | 4-Thiouridine | |||||||||
| CAS | 13957-31-8 | |||||||||
| Formula | C9H12N2O5S | |||||||||
| Molar Mass | 260.27 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Burger K, et al. 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response. RNA Biol. 2013 Oct;10(10):1623-30. |