PeptideDB

4-Thiouridine

CAS: 13957-31-8 F: C9H12N2O5S W: 260.27

4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits
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Bioactivity 4-Thiouridine is a ribonucleoside analog, it is widely used in RNA analysis and (m)RNA labeling. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response[1].
Invitro 4-thiouridine (0-10 μM) labels and purifies nascent rRNA without significantly affecting rRNA synthesis[1].4-thiouridine (≥50 μM) strongly inhibits production and processing of rRNA[1].
Name 4-Thiouridine
CAS 13957-31-8
Formula C9H12N2O5S
Molar Mass 260.27
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Burger K, et al. 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response. RNA Biol. 2013 Oct;10(10):1623-30.