Bioactivity | 4-Arm PEG-amine (MW 5000) is a PEG Linker. The reactive primary amine or NH2 rapidly react with aldehyde, ketone to form imine. Imine upon further reduction forms secondary amine via reductive amination. Amine reacts with activated carboxyl acid, NHS ester to form stable amide bonds. 4-Arm PEG reagents are useful crosslinking reagent and used for drug delivery[1]. |
CAS | 169501-65-9 |
Formula | (C2H4O)n(C2H4O)n(C2H4O)n(C2H4O)nC13H32N4O4 |
Molar Mass | 5000.00 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Roberts MJ, et al. Chemistry for peptide and protein PEGylation. Adv Drug Deliv Rev. 2002 Jun 17;54(4):459-76. |