| Bioactivity | 3-Hydroxymethyl-β-carboline antagonizes the anxiolytic and anticonvulsant actions of Diazepam and reverses the sedative action of Flurazepam. 3-Hydroxymethyl-β-carboline also antagonizes the cerebrovascular and cerebral metabolic depression produced by Flurazepam[1][2]. |
| CAS | 65474-79-5 |
| Formula | C12H10N2O |
| Molar Mass | 198.22 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Skolinick P, et al. 3-hydroxymethyl-beta-carboline antagonizes some pharmacologic actions of diazepam. Eur J Pharmacol. 1981 Feb 19;69(4):525-7. [2]. Hoffman WE, et al. Cerebrovascular and cerebral metabolic effects of flurazepam and a benzodiazepine antagonist, 3-hydroxymethyl-beta-carboline. Eur J Pharmacol. 1984 Nov 27;106(3):585-91. |
3-Hydroxymethyl-β-carboline
CAS: 65474-79-5 F: C12H10N2O W: 198.22
3-Hydroxymethyl-β-carboline antagonizes the anxiolytic and anticonvulsant actions of Diazepam and reverses the sedative
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