3-Hydroxy benzopyrene-d11_product_DataBase

Bioactivity	3-Hydroxy benzopyrene-d11is the deuterium labeled3-Hydroxy benzopyrene(HY-144950)[1]. 3-Hydroxy benzopyrene is a metabolite of Benzopyrene (HY-107377)[2].
Invitro	氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。
Name	3-Hydroxy benzopyrene-d11
CAS	1246819-35-1
Formula	C20HD11O
Molar Mass	279.38
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Bouchard M, et al. Benzo(a)pyrenediolepoxide-hemoglobin adducts and 3-hydroxy-benzo(a)pyrene urinary excretion profiles in rats subchronically exposed to benzo(a)pyrene. Arch Toxicol. 1995;69(8):540-6.

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