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3-Chlorogentisyl alcohol

CAS: 32744-80-2 F: C7H7ClO3 W: 174.58

3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.74 µM, an Ki value of 0
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Bioactivity 3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.74 µM, an Ki value of 0.58 µM. 3-Chlorogentisyl alcohol shows antiproliferative activity. 3-Chlorogentisyl alcohol has the potential for the research of anti-cancer and anti-inflammatory therapies[1].
Target IC50: 0.74 µM (β-glucuronidase)
Invitro 3-Chlorogentisyl alcohol (compound 1) (20 µM; 24 h) shows antiproliferative activity in Namalwa, U266 cells[1]. Cell Proliferation Assay[1] Cell Line:
Name 3-Chlorogentisyl alcohol
CAS 32744-80-2
Formula C7H7ClO3
Molar Mass 174.58
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. YichaoGe, et al. Exploring gabosine and chlorogentisyl alcohol derivatives from a marine-derived fungus as EcGUS inhibitors with informatic assisted approaches. European Journal of Medicinal Chemistry, 2022, 114699.