| Bioactivity | 3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.74 µM, an Ki value of 0.58 µM. 3-Chlorogentisyl alcohol shows antiproliferative activity. 3-Chlorogentisyl alcohol has the potential for the research of anti-cancer and anti-inflammatory therapies[1]. | |||||||||
| Target | IC50: 0.74 µM (β-glucuronidase) | |||||||||
| Invitro | 3-Chlorogentisyl alcohol (compound 1) (20 µM; 24 h) shows antiproliferative activity in Namalwa, U266 cells[1]. Cell Proliferation Assay[1] Cell Line: | |||||||||
| Name | 3-Chlorogentisyl alcohol | |||||||||
| CAS | 32744-80-2 | |||||||||
| Formula | C7H7ClO3 | |||||||||
| Molar Mass | 174.58 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. YichaoGe, et al. Exploring gabosine and chlorogentisyl alcohol derivatives from a marine-derived fungus as EcGUS inhibitors with informatic assisted approaches. European Journal of Medicinal Chemistry, 2022, 114699. |