| Bioactivity | 3-AQC, a piperazinylquinoxaline derivative, is a potent and competitive 5-HT3 receptor antagonist[1]. |
| Invitro | 3-AQC (化合物 7e) 的效力几乎比 Tropisetron (HY-B0072) 强 100 倍。在豚鼠回肠中对 2-methyl-5HT 的拮抗作用的 pA2 为10.2[1]。 |
| Name | 3-AQC |
| CAS | 201216-42-4 |
| Formula | C20H21N5O4 |
| Molar Mass | 395.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. A Monge, et al. Novel antagonists of 5-HT3 receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives. J Med Chem. 1993 Sep 17;36(19):2745-50. |