| Bioactivity | 2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract, resulting in amelioration of fever and nasal inflammation[1][2]. |
| Target | EC90: <0.35 μM (influenza virus A and B) |
| Name | 2′-Deoxy-2′-fluoroguanosine |
| CAS | 78842-13-4 |
| Formula | C10H12FN5O4 |
| Molar Mass | 285.23 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Tisdale M, et, al. Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine. Antimicrob Agents Chemother. 1995 Nov;39(11):2454-8. [2]. Jakeman KJ, et, al. Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets. Antimicrob Agents Chemother. 1994 Aug;38(8):1864-7. |
2′-Deoxy-2′-fluoroguanosine
CAS: 78842-13-4 F: C10H12FN5O4 W: 285.23
2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of
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