Bioactivity | 2B-(SP) is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). 2B-(SP) is readily phosphorylated by both the α and β isoforms of GSK-3[1]. |
Name | 2B-(SP) |
CAS | 186901-17-7 |
Sequence | Arg-Arg-Ala-Ala-Glu-Glu-Leu-Asp-Ser-Arg-Ala-Gly-{Ser(PO3H2)}-Pro-Gln-Leu |
Shortening | RRAAEELDSRAG-{Ser(PO3H2)}-PQL |
Formula | C71H123N26O29P |
Molar Mass | 1835.87 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. G I Welsh, et al. Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts.Anal Biochem. 1997 Jan 1;244(1):16-21. |