Bioactivity | 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells[1][2]. | ||||||||||||
Name | 20(S)-Hydroxycholesterol | ||||||||||||
CAS | 516-72-3 | ||||||||||||
Formula | C27H46O2 | ||||||||||||
Molar Mass | 402.65 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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