Bioactivity | 2-PAT, an analogue of Rasagiline and Selegiline, a reversible MAO-A inhibitor with an IC50 of 0.721 µM. 2-PAT is an inactivator of MAO-B with an IC50 of 14.6 µM. 2-PAT has the potential for Parkinson’s disease and depression research[1]. |
Name | 2-PAT |
CAS | 134467-58-6 |
Formula | C13H15N |
Molar Mass | 185.26 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Letitia Meiring, et al. The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase. Bioorg Med Chem Lett. 2022 Jul 1;67:128746. |