| Bioactivity | 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[1][2]. |
| In Vivo | 2-Iodoacetamide (2.0-10 mg; drinking; daily; 20-93 days) feeding always produces chronic deep ulcers in the secretory part of the rat stomach[2]. Animal Model: |
| Name | 2-Iodoacetamide |
| CAS | 144-48-9 |
| Formula | C2H4INO |
| Molar Mass | 184.96 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Peter G Hains, et al. The Impact of Commonly Used Alkylating Agents on Artifactual Peptide Modification. J Proteome Resq. 2017 Sep 1;16(9):3443-3447. [2]. J J LALICH. Iodoacetamide induced gastric ulcers in rats. Proc Soc Exp Biol Med. 1962 Apr;109:905-8. |