| Bioactivity | 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole (Compound APS) has anti-cancer activity in hepatocellular carcinoma (HCC) by repression of M2 polarization of Tumor-associated macrophages (TAMs). 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole can be isolated from Astragalus propinquus Schischk[1]. | |||||||||
| Name | 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole | |||||||||
| CAS | 89250-26-0 | |||||||||
| Formula | C10H7ClN2O2S | |||||||||
| Molar Mass | 254.69 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
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| Reference | [1]. Li C, et al. Astragalus polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages. Pharm Biol. 2021 Dec;59(1):1533-1539. |
2-(Chloromethyl)-4-(4-nitrophenyl)thiazole
CAS: 89250-26-0 F: C10H7ClN2O2S W: 254.69
2-(Chloromethyl)-4-(4-nitrophenyl)thiazole (Compound APS) has anti-cancer activity in hepatocellular carcinoma (HCC) by
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