| Bioactivity | 18A (HIV-1 inhibitor 18A) is a reversible broad-spectrum HIV-1 inhibitor. 18A exhibits broad inhibitory activity against multiple HIV-1 strains by blocking the function of Env[1]. |
| Target | HIV-1. |
| Invitro | 18A (0.01-10 µM; 40-44 h) 特异性抑制 HIV-1JR-FL 对人 PBMCs 的感染 (IC50 = 0.4 μM)[1]。 Cell Viability Assay[1] Cell Line: |
| Name | 18A |
| CAS | 331261-50-8 |
| Formula | C14H11N5O2S |
| Molar Mass | 313.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Herschhorn A, et al. A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry. Nat Chem Biol. 2014 Oct;10(10):845-52. |