Bioactivity | 17β-HSD10-IN-1 (compound 9) is an orally active inhibitor of 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) with blood-brain permeability. 17β-HSD10-IN-1 doesn't result additional effects for mitochondrial off-targets and cytotoxic or neurotoxic effects[1]. |
Target | 17β-HSD10 |
Name | 17β-HSD10-IN-1 |
CAS | 2316765-78-1 |
Formula | C16H13ClN4O3S |
Molar Mass | 376.82 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Benek O, et al. Development of submicromolar 17尾-HSD10 inhibitors and their in vitro and in vivo evaluation. Eur J Med Chem. 2023 Oct 5;258:115593.聽 |