Bioactivity | 15-epi-PGE1 is a stereoisomer of PGE1 but with less biological activity[2]. 15-epi-PGE1 is a non-competitive inhibitor for human placental 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) with an IC50 of 170 μM[1]. |
Target | 170 μM (15-PGDH) |
CAS | 20897-91-0 |
Formula | C20H34O5 |
Molar Mass | 354.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jarabak J, et al., Kinetic studies on a 15-hydroxyprostaglandin dehydrogenase from human placenta. Arch Biochem Biophys. 1976 Nov;177(1):245-54. [2]. MURAKAMI A, et al., Conformational analysis of prostaglandins. II. Most probable conformation of prostaglandin A, B, E, and F. Chemical and Pharmaceutical Bulletin. 1977 25(1):2870-2874 |