11β-HSD2-IN-2_product_DataBase

Bioactivity	11β-HSD2-IN-2 (compound 3) is a selective inhibitor for 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) with an IC50 of 300 nM[1].
Target	IC50: 300 nM (17β-HSD2 Inhibitor); 16100 nM (17β-HSD1 Inhibitor)
Invitro	11β-HSD2-IN-2 (0-100 μM) 在 HEK293 细胞中表现出中度的细胞毒性，LD50 大约为 25 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 11β-HSD2-IN-2 相关抗体: Cell Viability Assay[1] Cell Line:
CAS	1834601-37-4
Formula	C22H21NO2
Molar Mass	331.41
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Gargano EM, et al., Addressing cytotoxicity of 1,4-biphenyl amide derivatives: Discovery of new potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors. Bioorg Med Chem Lett. 2016 Jan 1;26(1):21-4.

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