| Bioactivity | 10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD50 is 8.8 mg/kg)[1]. |
| Target | IC50: 21 μM (Ras Farnesyltransferase) |
| CAS | 136803-89-9 |
| Formula | C24H20N4O7 |
| Molar Mass | 476.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Liu WC, et al. 10'-Desmethoxystreptonigrin, a novel analog of streptonigrin. J Antibiot (Tokyo). 1992 Apr;45(4):454-7. |
10'-Desmethoxystreptonigrin
CAS: 136803-89-9 F: C24H20N4O7 W: 476.44
10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonig
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