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1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one

CAS: 60798-06-3 F: C11H12N2O2 W: 204.23

1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one (Compound 2) has antiprion activity in ScN2a and F3 cells with IC50 va
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Bioactivity 1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one (Compound 2) has antiprion activity in ScN2a and F3 cells with IC50 values of 13 nM and 25 nM, respectively[1].
CAS 60798-06-3
Formula C11H12N2O2
Molar Mass 204.23
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Reference [1]. Kimata A, et al. New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation. J Med Chem. 2007 Oct 18;50(21):5053-6.