Bioactivity | (−)-N-Hydroxyapiosporamide (NHAP), an alkaloid, is an NF-κB inhibitor with potent antitumor activity in vitro and in vivo. (−)-N-Hydroxyapiosporamide can be used for the research of colorectal cancer (CRC)[1]. |
Name | (−)-N-Hydroxyapiosporamide |
CAS | 1205676-02-3 |
Formula | C24H31NO7 |
Molar Mass | 445.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Feng L, et al. The Natural Alkaloid (-)-N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex. J Nat Prod. 2023 Jun 23;86(6):1449-1462. |