Bioactivity | (±)-PPCC hemioxalate is a compound that has the ability to regulate the activity of the sigma-1 receptor. (±)-PPCC hemioxalate can selectively bind sigma-1 protein (s1), and then activate s1 receptor leading to dissociation of s1-BIP complex to regulate ER-mitochondrial calcium signaling, which plays an important role in cell bioenergy and cell survival. (±)-PPCC hemioxalate can be used to study sigma-1 receptors in cocaine addiction, forgetting, pain, depression, Alzheimer's disease, stroke, and cancer[1]. |
CAS | 932736-91-9 |
Formula | C24H29NO3.0.5C2H2O4 |
Molar Mass | 424.23 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sarpietro M G, et al. DSC investigation of the effect of the new sigma ligand PPCC on DMPC lipid membrane[J]. International Journal of Pharmaceutics, 2014, 469(1): 88-93. |