| Bioactivity | (±)-2-Propyl-4-pentenoic acid (4-en-VPA) is a major toxic metabolite of Valproic acid. (±)-2-Propyl-4-pentenoic acid exhibits neuroteratogenicity[1][2]. |
| Invitro | (±)-2-Propyl-4-pentenoic acid (1 mM; 26 h) induces approximately 50% of dysmorphogenic mouse embryos[2]. |
| Name | (±)-2-Propyl-4-pentenoic acid |
| CAS | 1575-72-0 |
| Formula | C8H14O2 |
| Molar Mass | 142.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. W Tang, et, al. A comparative investigation of 2-propyl-4-pentenoic acid (4-ene VPA) and its alpha-fluorinated analogue: phase II metabolism and pharmacokinetics. Drug Metab Dispos. 1997 Feb;25(2):219-27. [2]. Gofflot F, et, al. In vitro neuroteratogenicity of valproic acid and 4-en-VPA. Neurotoxicol Teratol. Jul-Aug 1995;17(4):425-35. |
(±)-2-Propyl-4-pentenoic acid
CAS: 1575-72-0 F: C8H14O2 W: 142.20
(±)-2-Propyl-4-pentenoic acid (4-en-VPA) is a major toxic metabolite of Valproic acid. (±)-2-Propyl-4-pentenoic acid e
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