| Bioactivity | (s)-PF-4136309 is the inactive isomer of PF-4136309 (HY-13245), and can be used as an experimental control. PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2. |
| Name | (s)-PF-4136309 |
| CAS | 1372407-07-2 |
| Formula | C29H31F3N6O3 |
| Molar Mass | 568.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xue CB, et al. Discovery of INCB8761/PF-4136309, a Potent, Selective, and Orally Bioavailable CCR2 Antagonist. ACS Med. Chem. Lett., 2011, 2 (12), pp 913-918. |
(s)-PF-4136309
CAS: 1372407-07-2 F: C29H31F3N6O3 W: 568.59
(s)-PF-4136309 is the inactive isomer of PF-4136309 (HY-13245), and can be used as an experimental control. PF-4136309 i
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