PeptideDB

(all-E)-UAB30

CAS: 205252-59-1 F: C20H22O2 W: 294.39

(all-E)-UAB30 (UAB30) is an retinoid X receptor (RXR) selective agonist.(all-E)-UAB30 shows anti-proliferation activityf
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Bioactivity (all-E)-UAB30 (UAB30) is an retinoid X receptor (RXR) selective agonist.(all-E)-UAB30 shows anti-proliferation activity for MyLa, HuT 78, and HH cells with the IC50 of 34.7, 5.1, and 22.4 μM respectively[1][2].
CAS 205252-59-1
Formula C20H22O2
Molar Mass 294.39
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Adele P. Williams, et al. UAB30, A Novel Rexinoid Agonist, Decreases Stemness In Group 3 Medulloblastoma Human Cell Line Xenografts. Transl Oncol. 2019 Oct;12(10):1364-1374. [2]. Chu-Fang Chou, et al. The Retinoid X Receptor Agonist, 9-cis UAB30, Inhibits Cutaneous T-cell Lymphoma Proliferation Through the SKP2-p27kip1 Axis. J Dermatol Sci. 2018 Jun; 90(3): 343–356.