Bioactivity | (Val3,Pro8)-Oxytocin is the Gq-dependent pathway agonist. (Val3,Pro8)-Oxytocin is also a weaker agonist for the β-arrestin engagement and endocytosis toward the oxytocin receptor (OXTR)[1]. |
Name | (Val3,Pro8)-Oxytocin |
CAS | 2134138-89-7 |
Sequence | Cys-Tyr-Val-Gln-Asn-Cys-Pro-Pro-Gly-NH2 (Disulfide bridge: Cys1-Cys6) |
Shortening | CYVQNCPPG-NH2 (Disulfide bridge: Cys1-Cys6) |
Formula | C41H60N12O12S2 |
Molar Mass | 977.12 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Parreiras-E-Silva LT, et, al. Functional New World monkey oxytocin forms elicit an altered signaling profile and promotes parental care in rats. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9044-9049. |