| Bioactivity | (Rac)-Tivantinib is the inactive isomer of Tivantinib (HY-50686), and can be used as an experimental control. Tivantinib is a highly selective c-Met tyrosine kinase inhibitor with a Ki of 355 nM. | ||||||||||||
| Name | (Rac)-Tivantinib | ||||||||||||
| CAS | 1239986-50-5 | ||||||||||||
| Formula | C23H19N3O2 | ||||||||||||
| Molar Mass | 369.42 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Bai YL, et al. Quantitative analysis of tivantinib in rat plasma using ultra performance liquid chromatography with tandem mass spectrometry. J Pharm Biomed Anal. 2016 Jul 15;126:98-102. [2]. Munshi N, et al. ARQ 197, a novel and selective inhibitor of the human c-Met receptor tyrosine kinase with antitumor activity. Mol Cancer Ther. 2010 Jun;9(6):1544-53. |
(Rac)-Tivantinib
CAS: 1239986-50-5 F: C23H19N3O2 W: 369.42
(Rac)-Tivantinib is the inactive isomer of Tivantinib (HY-50686), and can be used as an experimental control. Tivantinib
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