Bioactivity | (R)-PF-06256142 is the R enantiomer of PF-06256142 with low active. PF-06256142 is a potent and selective orthosteric D1 receptor agonist that can reduce receptor desensitization relative to dopamine and other catechol-containing agonists[1]. | ||||||||||||
Name | (R)-PF-06256142 | ||||||||||||
CAS | 1609583-15-4 | ||||||||||||
Formula | C21H16N4O2 | ||||||||||||
Molar Mass | 356.38 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Davoren JE, et al. Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization. J Med Chem. 2018;61(24):11384-11397. |