| Bioactivity | (E/Z)-4,4'-Dicyanostilbene is the inactive isomer of 4,4'-Dicyanostilbene (HY-W112166A), and can be used as an experimental control. 4,4'-Dicyanostilbene (compound 43) is a potent antimalarial agent against the Dd2 strain, with an EC50 of 27 nM. 4,4'-Dicyanostilbene exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA)[1]. | ||||||||||||
| Name | (E/Z)-4,4'-Dicyanostilbene | ||||||||||||
| CAS | 6292-62-2 | ||||||||||||
| Formula | C16H10N2 | ||||||||||||
| Molar Mass | 230.26 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Kyei-Baffour K, et, al. Natural product-inspired aryl isonitriles as a new class of antimalarial compounds against drug-resistant parasites. Bioorg Med Chem. 2020 Oct 1;28(19):115678. |
(E/Z)-4,4'-Dicyanostilbene
CAS: 6292-62-2 F: C16H10N2 W: 230.26
(E/Z)-4,4'-Dicyanostilbene is the inactive isomer of 4,4'-Dicyanostilbene (HY-W112166A), and can be used as an experimen
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