Bioactivity | (7S)-BAY-593 is the S-enantiomer of BAY-593 (HY-161573). BAY-593 is an orally active GGTase-I inhibitor. BAY-593 has anti-tumor activity and blocks YAP1/TAZ signaling in vivo[1]. | ||||||||||||
CAS | 2413068-25-2 | ||||||||||||
Formula | C26H31F3N2O3 | ||||||||||||
Molar Mass | 476.53 | ||||||||||||
Appearance | 固体 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Graham K, et al. Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol. 2024 Mar 19:S2451-9456(24)00087-4. |