Bioactivity | (-)-Mcl-1 inhibitor 21 (Example 1-38) is a Mcl-1 inhibitor with an IC50 of 7.51 μM. (-)-Mcl-1 inhibitor 21 exhibits proapototic and anti-proliferation activities against SUDHL5 and SUDHL10 cell lines and can be utilized in cancer research[1]. |
CAS | 2157421-24-2 |
Formula | C32H33N3O4 |
Molar Mass | 523.62 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sarah W, et al. Macrocyclic indole derivatives. WO2017198341A1. 2017-11-23 |