| Bioactivity | (-)-Halofantrine ((-)-SKF-102886 free base; (-)-WR-171669) is an inhibitor of the malignant malaria parasite (P. falciparum) and targets multidrug-resistant P. falciparum. The pharmacokinetic parameters of (-)-Halofantrine in rats vary depending on the route of administration, distinguishing it from other isomers[1]. |
| Target | P. falciparum |
| In Vivo | Halofantrine HCl在 大鼠空腹状态下的药代动力学数据[1][1]Route |
| CAS | 66051-76-1 |
| Formula | C26H30Cl2F3NO |
| Molar Mass | 500.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Brocks DR, et al. Pharmacokinetics of halofantrine in the rat: stereoselectivity and interspecies comparisons. Biopharm Drug Dispos. 1999 Apr;20(3):165-9. |
(-)-Halofantrine
CAS: 66051-76-1 F: C26H30Cl2F3NO W: 500.42
(-)-Halofantrine ((-)-SKF-102886 free base; (-)-WR-171669) is an inhibitor of the malignant malaria parasite (P. falcipa
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