| Bioactivity | (+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride, benzyltetrahydroisoquinoline alkaloid isolated from a variety of plant sources. (+)-Coclaurine hydrochloride has anti-aging activity[1][2]. |
| In Vivo | An intracerebroventricular injection of (+)-Coclaurine (d-Coclaurine; 50 μg) hydrochloride produces a slight increase in 3,4-dihydroxyphenylacetic acid level and a significant increase in homovanillic acid level in the mouse striatum. (+)-Coclaurine hydrochloride blocks postsynaptic but not presynaptic dopamine receptors in the mouse striatum[2]. |
| Name | (+)-Coclaurine hydrochloride |
| CAS | 19894-19-0 |
| Formula | C17H20ClNO3 |
| Molar Mass | 321.80 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. [1]Siva S Panda, et al. Protective effects of Aporosa octandra bark extract against D-galactose induced cognitive impairment and oxidative stress in mice. Heliyon. 2018 Nov 30;4(11):e00951. [2]. H Watanabe, et al. Effects of d-coclaurine and d-reticuline, benzyltetrahydroisoquinoline alkaloids, on levels of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the mouse striatum. J Pharmacobiodyn. 1983 Oct;6(10):793-6. |
(+)-Coclaurine hydrochloride
CAS: 19894-19-0 F: C17H20ClNO3 W: 321.80
(+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride, benzyltetrahydroisoquinoline alkaloid isolated from a variety of plan
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