Pinosylvin monomethyl ether has antibacterial and antifungal activity.

Physicochemical Properties

Molecular Formula	C15H14O2
Molecular Weight	226.27
Exact Mass	226.099
CAS #	35302-70-6
PubChem CID	5281719
Appearance	White to off-white solid powder
Density	1.2±0.1 g/cm3
Boiling Point	405.8±24.0 °C at 760 mmHg
Flash Point	245.6±7.8 °C
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.662
LogP	4.34
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Heavy Atom Count	17
Complexity	243
Defined Atom Stereocenter Count	0
SMILES	COC1=CC(=CC(=C1)O)/C=C/C2=CC=CC=C2
InChi Key	JVIXPWIEOVZVJC-BQYQJAHWSA-N
InChi Code	InChI=1S/C15H14O2/c1-17-15-10-13(9-14(16)11-15)8-7-12-5-3-2-4-6-12/h2-11,16H,1H3/b8-7+
Chemical Name	3-methoxy-5-[(E)-2-phenylethenyl]phenol
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: This product requires protection from light (avoid light exposure) during transportation and storage.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References	[1]. Lindberg LE, Willför SM, Holmbom BR. Antibacterial effects of knotwood extractives on paper mill bacteria. J Ind Microbiol Biotechnol. 2004;31(3):137-147. [2]. Structure-fungicidal properties of some 3- and 4-hydroxylated stilbenes and bibenzyl analogues. Phytochemistry, 1992, 31(11):3801–3806.
Additional Infomation	Pinosylvin methyl ether is a stilbenoid. Pinosylvin methyl ether has been reported in Pinaceae, Pinus pinea, and other organisms with data available.

Solubility Data

Solubility (In Vitro)

DMSO : 100 mg/mL (441.95 mM)

Solubility (In Vivo)

Solubility in Formulation 1: ≥ 2.5 mg/mL (11.05 mM) (saturation unknown) in 10% DMSO + 90% (20% SBE-β-CD in Saline) (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of 20% SBE-β-CD physiological saline solution and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C，1 week): Dissolve 2 g SBE-β-CD in 10 mL saline to obtain a clear solution. Solubility in Formulation 2: ≥ 2.5 mg/mL (11.05 mM) (saturation unknown) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one), clear solution. For example, if 1 mL of working solution is to be prepared, you can add 100 μL of 25.0 mg/mL clear DMSO stock solution to 900 μL of corn oil and mix evenly.  (Please use freshly prepared in vivo formulations for optimal results.)

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	4.4195 mL	22.0975 mL	44.1950 mL
	5 mM	0.8839 mL	4.4195 mL	8.8390 mL
	10 mM	0.4419 mL	2.2097 mL	4.4195 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.