Glucocorticoid receptor drug-linke 1 is a drug-linker conjugate that can be used to synthesize ADCs targeting BDCA2.

Physicochemical Properties

Molecular Formula	C35H40NO9P
Molecular Weight	649.67
CAS #	3048601-02-8
Appearance	White to off-white solid powder
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: (1). This product requires protection from light (avoid light exposure) during transportation and storage.(2). Please store this product in a sealed and protected environment (e.g. under nitrogen), avoid exposure to moisture.
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1]. Anti-bdca2 antibody-drug conjugate and use thereof. WO2024140838.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	1.5392 mL	7.6962 mL	15.3924 mL
	5 mM	0.3078 mL	1.5392 mL	3.0785 mL
	10 mM	0.1539 mL	0.7696 mL	1.5392 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.