GGFG-PAB-Exatecan TFA consists of the toxin molecule Exatecan and the linker GGFG-PAB and can be used as a drug-linker conjugate for the synthesis of ADC molecules.

Physicochemical Properties

Molecular Formula	C49H48F4N8O12
Molecular Weight	1016.95
Related CAS #	GGFG-PAB-Exatecan;251459-32-2
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

ln Vitro	ADCs consist of an antibody to which the ADC cytotoxin is attached via an ADC linker.
References	[1]. Epsilon-poly-l-lysine-based drug conjugate, intermediate thereof, and application thereof. WO2023078464.

Solubility Data

Preparing Stock Solutions		1 mg	5 mg	10 mg
	1 mM	0.9833 mL	4.9167 mL	9.8333 mL
	5 mM	0.1967 mL	0.9833 mL	1.9667 mL
	10 mM	0.0983 mL	0.4917 mL	0.9833 mL

*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles.