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Fli-1-IN-1 (compound 21) fumarate is a FLI1 targeting agent that can directly bind to and inhibit EWS-FLI1 protein interaction. EWS-FLI1 is able to bind to RNA helicase A, and Fli-1-IN-1 fumarate inhibits EWS-FLI1 and has potential anticancer activity.
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Physicochemical Properties
| Molecular Formula |
C39H48N2O10
|
| Molecular Weight |
704.81
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| Related CAS # |
Fli-1-IN-1;3027140-81-1
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| Storage |
Powder-20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
|
| Shipping Condition |
Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
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Biological Activity
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Solubility Data
| Preparing Stock Solutions |
|
1 mg |
5 mg |
10 mg |
| 1 mM |
1.4188 mL |
7.0941 mL |
14.1882 mL |
| 5 mM |
0.2838 mL |
1.4188 mL |
2.8376 mL |
| 10 mM |
0.1419 mL |
0.7094 mL |
1.4188 mL |
*Note: Please select an appropriate solvent for the preparation of stock solution based on your experiment needs. For most products, DMSO can be used for preparing stock solutions (e.g. 5 mM, 10 mM, or 20 mM concentration); some products with high aqueous solubility may be dissolved in water directly. Solubility information is available at the above Solubility Data section. Once the stock solution is prepared, aliquot it to routine usage volumes and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles. |
