ALDH1A1/2-IN-1 is an ALDH1A1 and ALDH1A2 inhibitor that can be used to prevent spermatogenesis.

Physicochemical Properties

CAS #	2445840-25-3
Appearance	White to off-white solid powder
HS Tariff Code	2934.99.9001
Storage	Powder-20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Shipping Condition	Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)

Biological Activity

References

[1].Goldstein AS, et, al. Inhibitor compounds for male contraception. WO2020123855A1.

Solubility Data

Solubility (In Vitro)

DMSO :~200 mg/mL (~406.14 mM; with sonication)

Solubility (In Vivo)

Solubility in Formulation 1: 5 mg/mL (10.15 mM) in 10% DMSO + 90% Corn Oil (add these co-solvents sequentially from left to right, and one by one),clear solution; with ultrasonication. For example, if 1 mL of working solution is to be prepared,you can add 100 μL of 50.0 mg/mL clear DMSO stock solution and add it to 900 μL corn oil and mix well.  (Please use freshly prepared in vivo formulations for optimal results.)