| Description | YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 ( mPGES-1; IC 50 =3.4 μM) and 5-lipoxygenase ( 5-LOX; IC 50 =6.5 μM). YS121 dose-dependently reduces the production of PGE2 with EC 50 =12 μM in IL-1β-stimulated A549 cells [1]. |
| molecular weight | 407.96 |
| Molecular formula | C20H26ClN3O2S |
| CAS | 916482-17-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |