PeptideDB

TASP0376377

CAS No.: 1233246-60-0

TASP0376377 is a potent antagonist of CRTH2.
Sales Email:peptidedb@qq.com

This product is for research use only, not for human use. We do not sell to patients.

Description TASP0376377 is a potent antagonist of CRTH2.
Synonyms TASP-0376377, TASP 0376377
molecular weight 479.31
Molecular formula C25H16Cl2N2O4
CAS 1233246-60-0
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Nishikawa-Shimono R, Sekiguchi Y, Koami T, Kawamura M, Wakasugi D, Watanabe K, Wakahara S, Kimura K, Yamanobe S, Takayama T. Isoquinoline derivatives as potent CRTH2 antagonists: design, synthesis and SAR. Bioorg Med Chem. 2013 Dec 15;21(24):7674-85. doi: 10.1016/j.bmc.2013.10.025. Epub 2013 Oct 30. PubMed PMID: 24216094. 2. Nishikawa-Shimono R, Sekiguchi Y, Koami T, Kawamura M, Wakasugi D, Watanabe K, Wakahara S, Matsumoto K, Takayama T. Isoquinoline derivatives as potent CRTH2 receptor antagonists: synthesis and SAR. Bioorg Med Chem Lett. 2012 May 1;22(9):3305-10. doi: 10.1016/j.bmcl.2012.03.009. Epub 2012 Mar 10. PubMed PMID: 22469703.