| Description | L 651580 is a bioactive chemical. |
| Synonyms | L651580, L-651580 |
| molecular weight | 345.48 |
| Molecular formula | C21H31NO3 |
| CAS | 103335-44-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Lu Q, Chen WY, Zhu ZY, Chen J, Xu YC, Kaewpet M, Rukachaisirikul V, Chen LL, Shen X. L655,240, acting as a competitive BACE1 inhibitor, efficiently decreases β-amyloid peptide production in HEK293-APPswe cells. Acta Pharmacol Sin. 2012 Dec;33(12):1459-68. doi: 10.1038/aps.2012.74. Epub 2012 Jul 30. PubMed PMID: 22842730; PubMed Central PMCID: PMC4001842. 2. Weinberg ML, Moreira E, Weinberg J. Arachidonic acid products-mediated contraction induced by bradykinin in relaxed mesenteric arterial rings from Holtzman rats. Eur J Pharmacol. 1997 Feb 12;320(2-3):145-50. PubMed PMID: 9059847. 3. Campos AH, Calixto JB. Mechanisms involved in the contractile responses of kinins in rat portal vein rings: mediation by B1 and B2 receptors. J Pharmacol Exp Ther. 1994 Feb;268(2):902-9. PubMed PMID: 8114004. 4. Tardif M, Bergeron Y, Beauchamp D, Bergeron MG. Increased renal uptake of gentamicin in endotoxemic rats receiving concomitant thromboxane A2 antagonist therapy. Antimicrob Agents Chemother. 1993 Dec;37(12):2727-32. PubMed PMID: 8109943; PubMed Central PMCID: PMC192792. |