| Description | Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid and nucleotide intermediates. |
| Target activity | XO:6.5 nM |
| Synonyms | 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid |
| molecular weight | 314.24 |
| Molecular formula | C16H8F2N2O3 |
| CAS | 1071970-13-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 10 mg/mL (31.82 mM) |
| References | 1. Shimizu K, et al. Preparation of (aza)indole derivatives as xanthine oxidase inhibitors. WO2008126898 A1. |