| Description | Xanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor (IC50 : 55 nM).Xanthine oxidoreductase-IN-5 may be used in studies of acute hyperuricemia. |
| In vivo | Xanthine oxidoreductase-IN-5 (Compound IIIa)（5 mg/kg；口服）在给药后5小时内对急性高尿酸血症小鼠展现了降低尿酸的效果。[1] |
| Target activity | Xanthine oxidoreductase:55 nM |
| molecular weight | 323.35 |
| Molecular formula | C17H17N5O2 |
| CAS | 1026652-90-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (139.17 mM) |
| References | 1. Peng W, et al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2023;246:114947. |
Xanthine oxidoreductase-IN-5
CAS No.: 1026652-90-3
Xanthine oxidoreductase-IN-5 is an orally active xanthine oxidoreductase (XOR) inhibitor (IC50 : 55 nM).Xanthine oxidore
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