Description | WRW4 TFA (878557-55-2 free base) is a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC50 of 0.23 μM. WRW4 TFA(878557-55-2 free base) specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide. |
Target activity | FPRL1:0.23 μM |
Synonyms | WRW4 |
molecular weight | 1218.29 |
Molecular formula | C63H66F3N15O8 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility | H2O: 1 mg/mL DMSO: 10 mM |
References | 1. Bae et al (2004) Identification of peptides that antagonize formyl peptide receptor-like 1-mediating signaling. J.Immunol. 173 607 PMID: |