| Description | Hastatoside and verbenalin are major sleep-promoting components of V. officinalis. Hastatoside has anti-inflammatory activity. |
| In vivo | 使用马鞭草（Verbena officinalis，简称V. officinalis）制成的草本茶，传统上被用于治疗失眠和其它神经症状。研究通过电脑脑电图分析，评估了hastatoside、verbenalin和verbascoside（分别为V. officinalis主要的iridoids成分hastatoside与verbenalin，以及polyphenol成分verbascoside）的促睡眠活性。结果显示，hastatoside (0.64 mmol/kg体重) 和 verbenalin (1.28 mmol/kg体重) 在20.00时（熄灯时间）口服后约3-5小时，能在23.00至08.00的9小时内分别使非快速眼动睡眠总时长增加81%和42%。两种化合物均增强了非快速眼动睡眠期间的delta活动。然而，verbascoside对睡眠量没有影响。因此，hastatoside和verbenalin是V. officinalis的主要促睡眠成分。 |
| Synonyms | 戟叶马鞭草苷 |
| molecular weight | 404.37 |
| Molecular formula | C17H24O11 |
| CAS | 50816-24-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 80 mg/mL (197.83 mM) |
| References | 1. Makino Y , Kondo S , Nishimura Y , et al. Hastatoside and verbenalin are sleep‐promoting components in Verbena officinalis[J]. Sleep and Biological Rhythms, 2009, 7. |