| Description | VRT-325 can repair folding defects by promoting dimerization of the two NBDs or by promoting folding of the TMD.VRT-325 accelerates the healing rate of CF cell monolayers. |
| Synonyms | CFcor 325, VRT-534, CFcor325, VRT 325, VRT325, CF-106951, CFcor-325 |
| molecular weight | 510.65 |
| Molecular formula | C27H34N4O4S |
| CAS | 815592-21-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (88.12 mM) |
| References | 1. Wang Y, et al. Modulating the folding of P-glycoprotein and cystic fibrosis transmembrane conductance regulator truncation mutants with pharmacological chaperones. Mol Pharmacol. 2007 Mar;71(3):751-8. |