| Description | DLPC is an LRH-1 agonist ligand. DLPC is a phospholipid for biological study[1][2]. |
| In vivo | DLPC处理在小鼠肝脏中诱导胆酸生物合成酶的活性,提高胆酸水平,并降低肝三酸甘油酯与血清葡萄糖浓度。DLPC处理还减少肝脏脂肪变性,并在两种胰岛素抵抗的小鼠模型中改善葡萄糖稳态[2]。 |
| molecular weight | 621.83 |
| Molecular formula | C32H64NO8P |
| CAS | 18194-25-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | Ethanol: 99 mg/mL (159.20 mM), Sonication is recommended. DMSO: 7.14 mg/mL (11.48 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) |
| References | 1. Matthew E Nipper, et al. Detection of liposome membrane viscosity perturbations with ratiometric molecular rotors. Biochimie. 2011 Jun;93(6):988-94. 2. Jae Man Lee, et al. A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature. 2011 May 25;474(7352):506-10. |